Study shows improvements to chemical sensing chip that aims to quickly and accurately identify drugs and other trace chemicals — ScienceDaily


College at Buffalo researchers are reporting an development of a chemical sensing chip that would result in handheld gadgets that detect hint chemical compounds — every thing from illicit medicine to air pollution — as shortly as a breathalyzer identifies alcohol.

The chip, which additionally might have makes use of in meals security monitoring, anti-counterfeiting and different fields the place hint chemical compounds are analyzed, is described in a examine that seems on the quilt of the Dec. 17 version of the journal Superior Optical Supplies.

“There’s a nice want for moveable and cost-effective chemical sensors in lots of areas, particularly drug abuse,” says the examine’s lead writer Qiaoqiang Gan, PhD, professor {of electrical} engineering within the UB Faculty of Engineering and Utilized Sciences.

The work builds upon earlier analysis Gan’s lab led that concerned making a chip that traps mild on the edges of gold and silver nanoparticles.

When organic or chemical molecules land on the chip’s floor, a few of the captured mild interacts with the molecules and is “scattered” into mild of latest energies. This impact happens in recognizable patterns that act as fingerprints of chemical or organic molecules, revealing details about what compounds are current.

As a result of all chemical compounds have distinctive light-scattering signatures, the expertise might finally be built-in right into a handheld system for detecting medicine in blood, breath, urine and different organic samples. It may be integrated into different gadgets to establish chemical compounds within the air or from water, in addition to different surfaces.

The sensing methodology is named surface-enhanced Raman spectroscopy (SERS).

Whereas efficient, the chip the Gan group beforehand created wasn’t uniform in its design. As a result of the gold and silver was spaced inconsistently, it might make scattered molecules troublesome to establish, particularly in the event that they appeared on completely different areas of the chip.

Gan and a crew of researchers — that includes members of his lab at UB, and researchers from the College of Shanghai for Science and Know-how in China, and King Abdullah College of Science and Know-how in Saudi Arabia — have been working to treatment this shortcoming.

The crew used 4 molecules (BZT, 4-MBA, BPT, and TPT), every with completely different lengths, within the fabrication course of to manage the scale of the gaps in between the gold and silver nanoparticles. The up to date fabrication course of is predicated upon two strategies, atomic layer deposition and self-assembled monolayers, versus the extra frequent and costly methodology for SERS chips, electron-beam lithography.

The result’s a SERS chip with unprecedented uniformity that’s comparatively cheap to supply. Extra importantly, it approaches quantum-limit sensing capabilities, says Gan, which was a problem for typical SERS chips

“We expect the chip can have many makes use of along with handheld drug detection gadgets,” says the primary writer of this work, Nan Zhang, PhD, a postdoctoral researcher in Gan’s lab. “For instance, it could possibly be used to evaluate air and water air pollution or the security of meals. It could possibly be helpful within the safety and protection sectors, and it has large potential in well being care.”

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Materials offered by University at Buffalo. Unique written by Cory Nealon. Be aware: Content material could also be edited for model and size.



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